A Rat Model of Intracerebral Hemorrhage Permitting Hematoma Aspiration plus Intralesional Injection
نویسندگان
چکیده
منابع مشابه
Intracerebral hemorrhage in the rat: effects of hematoma aspiration.
BACKGROUND AND PURPOSE Deep intracerebral hemorrhage is associated with considerable mortality and morbidity, but the value of surgical therapy is debatable. The purpose of this study was to evaluate whether aspiration of the hematoma in a rodent model of intracerebral hemorrhage could improve final neurological outcome. METHODS Intracerebral hemorrhage was induced in 2 groups of rats by inje...
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Intracerebral hemorrhage (ICH), the most devastating form of stroke, has no specific therapy proven to improve outcome by randomized controlled trial. Location and baseline hematoma volume are strong predictors of mortality, but are nonmodifiable by the time of diagnosis. Expansion of the initial hematoma is a further marker of poor prognosis that may be at least partly preventable. Several ris...
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Recent case reports suggest that dopamine (DA) replacement may reduce behavioral deficits resulting from hemorrhages along the nigrostriatal tract. In the rat model of intracerebral hemorrhage (ICH), behavioral deficits are first evident on day 1, with return to near control levels by day 28. The current study was conducted to determine if striatal dopamine alterations are correlated with behav...
متن کاملIntracerebral Hemorrhage Following Evacuation of a Chronic Subdural Hematoma
Burr hole drainage has been widely used to treat chronic subdural hematomas (SDH), and most of them are easily treated by simple trephination and drainage. However, various complications, such as, hematoma recurrence, infection, seizure, cerebral edema, tension pneumocephalus and failure of the brain to expand due to cerebro-cranial disproportion may develop after chronic SDH drainage. Among th...
متن کاملStereotactic Hematoma Removal of Spontaneous Intracerebral Hemorrhage through Parietal Approach
OBJECTIVE To determine the advantages of parietal approach compared to Kocher's point approach for spontaneous, oval-shaped intracerebral hemorrhage (ICH) with expansion to the parietal region. METHODS We divided patients into two groups : group A had burr holes in the parietal bone and group B had burr holes at Kocher's point. The hematoma volume, Glasgow coma scale (GCS) score, and modified...
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ژورنال
عنوان ژورنال: Experimental Animals
سال: 2013
ISSN: 1341-1357,1881-7122
DOI: 10.1538/expanim.62.63